THE MECHANISMS AND CLINICAL POTENTIAL OF COLLATERAL SENSITIVITY IN MYCOBACTERIUM TUBERCULOSIS: A LITERATURE REVIEW

The mechanisms and clinical potential of collateral sensitivity in Mycobacterium tuberculosis: A literature review

Tuberculosis (TB) is a global health issue, and the increasing resistance to anti-tuberculosis therapy (ATT) highlights the need for innovative treatment regimens.Among the different collateral effects of resistance development, collateral sensitivity (CS) is a phenomenon in which drug-resistant mutants display increased susceptibility to other dru

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Dismal salvage of testicular torsion: A call to action!

Background: Testicular ischaemia and infarction in cases of torsion depend on the duration and degree of twisting.Early evaluation and treatment are associated with high salvage reports.Objective: To determine the salvage rates of testicular torsion in selected hospitals at the Coast Province of Kenya Design: A retrospective study of patients manag

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Molecular simulations and Markov state modeling reveal the structural diversity and dynamics of a theophylline-binding RNA aptamer in its unbound state.

RNA aptamers are oligonucleotides that bind with high specificity and affinity to target ligands.In the absence of bound ligand, secondary structures of RNA aptamers are generally stable, but single-stranded and loop regions, including ligand binding sites, lack defined structures and exist as ensembles of conformations.For example, the well-charac

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Z-EMATOLOGY IN TURKEY

In alignment with this vision, we are excited to introduce a new initiative: voyage et cie discount code Z-Ematology.This concept is designed to bridge the gap between Generation Z and the evolving field of hematology.The new generation brings fresh perspectives and skills, especially in areas such as artificial intelligence, puffy spa headband big

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